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Healive® - Inactivated Hepatitis A Vaccine
Healive is the 1st inactivated hepatitis A vaccine developed by Chinese scientists with their own IPRs. It ended the history of having no technology for manufacturing inactivated Hepatitis A vaccine in China. Healive gained the state certificate as a new drug in 1999 and was launched in 2002.
No preservative
Healive is a purified inactivated Hepatitis A vaccine without any preservative.
Fast, efficient and long-lasting immune effectiveness
100% seroconversion after two-dose regimen. Healive has the same efficiency and long-lasting immune effectiveness with Havrix. If calculated according to the international Van Damme formula, Healive can provide protection for more than 20 years.
 
Immunogenicity in Children group
 
Immunogenicity in Adult group
Safety
| Systemic Reaction Local Reaction |
| Vaccine |
Dosage |
Fever |
Others |
Redness &
swelling |
Pain |
Function |
Healive
(500U) |
1 |
1.75% |
0 |
3.51% |
1.75% |
Normal |
Havrix
(1440EL.U) |
1 |
5.26% |
3.51% |
10.53% |
12.28% |
Normal |
Healive
(500U) |
2 |
3.51% |
0 |
3.51% |
1.75% |
Normal |
Havrix
(1440EL.U) |
2 |
5.26% |
0 |
7.02% |
0 |
Normal |
| Comparison Adverse Effects Between Healive and Havrix in Adult |
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Owing to the advanced manufacturing process, Healive is fully purified without any preseruative and the virus is thoroughly inactivated.
Packed in pre-filled syringe with painless needle purchased from BD company, Healive is very convenient to be injected and painless.
Healive has fairly low adverse reactions, mainly slight fever, with temperature not over 37.5 ℃ and lasting no more than 24 hours; local red and emblem. The 2nd injection will be even more comfortable.
Stability
Long shelf life，at least 2.5 years under the condition of 2-8 ℃ and 32 days under the condition of 37 ℃, with all tests still in full compliance with quality specifications.
Adaptability
◇ Children above one year old ; primary school to university students
◇ Food and beverage handlers, hotel staffs
◇ Employees of kinder gardens and board schools
◇ Travelers
◇ Military people
◇ People close to Hepatitis A patients
◇ HBsAg carriers
◇ People with frequent blood infusions, drug addicts using vein injection,and homosexuals
◇ Others at risk |
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Administration and dosage
Two doses only. Month 0 and month 6th.Children from 1 to 15 years old injected with 0.5ml/250u, adults over the age of 16 years injected with 1.0ml/500u.
Precautions
- Take survey about illness history; avoid to be inoculated after getting prohibited diseases.
- Inject the vaccine into upper arm deltoid muscle by intramuscularly route and avoid to be injected under skin.
- Shake before use, avoid causing side effects.
Store and transprort
Store and transport between 2℃ to 8℃, do not freeze.
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